SNAIL Antikörper (N-Term)

Produktnummer ABIN2777859

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SNAIL in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Meerschweinchen, Pferd und Rind (Kuh).

Kurzübersicht für SNAIL Antikörper (N-Term) (ABIN2777859)

Target: SNAIL (SNAI1)

Reaktivität: Human, Ratte, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SNAIL Antikörper

Bindungsspezifität: N-Term

Sequenz: RKPSDPNRKP NYSELQDSNP EFTFQQPYDQ AHLLAAIPPP EILNPTASLP

Homologie: Cow: 77%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SNAI1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNAI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1

Hintergrund: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Alias Symbols: SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
Protein Interaction Partner: MTUS2, KRT31, TRIM23, ACTN2, MID2, NOTCH2NL, KRTAP10-3, KRT40, FBXL5, EZH2, RNF2, RING1, LATS2, UBC, BTRC, TP53, MDM2, GSK3B, HDAC1, CHD4, KDM1A, HDAC3, HDAC2, RCOR1, FBXL14, NOTCH1, HIST1H3A, EGR1, AJUBA, Sin3a, HOXD4, SUZ12, CTDSP1, CTDSPL, CTDSP2, QRIC
Protein Size: 264

Molekulargewicht: 29 kDa

Gen-ID: 6615

NCBI Accession: NM_005985, NP_005976

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling